Negentropy anomalies of borehole strain associated with the Wenchuan earthquake are analysed. The cumulative anomalies are studied on both large and small scales. Through a comparison discussion, we compare the cumulative anomalies of different time periods and stations with those at the Guza station during the study period and preliminarily exclude meteorological factors. We suspect negentropy anomalies at the Guza station to have recorded abnormal changes related to the Wenchuan earthquake.